 |
Case Report
Microvascular injury in the appendix of a pediatric patient with history of COVID-19 infection: A case report
1 Senior Histopathology resident, Pathology Department, Salmaniya Medical Complex, Manama, Kingdom of Bahrain
2 Senior Histopathology consultant, Pathology Department, Salmaniya Medical Complex, Manama, Kingdom of Bahrain
Address correspondence to:
Maryam Fadhel Hammad
Villa 2006, Road 5059, Block 450, Manama,
Kingdom of Bahrain
Message to Corresponding Author
Article ID: 100101Z06MH2021
Access full text article on other devices
Access PDF of article on other devices
How to cite this article
Hammad MF, Malik AK. Microvascular injury in the appendix of a pediatric patient with history of COVID-19 infection: A case report. Case Rep Int 2021;10:100101Z06MH2021.ABSTRACT
Introduction: A novel coronavirus (SARS-CoV-2) infection has emerged in the world causing a pandemic disease with severe forms of acute respiratory failure along with other organs manifestations. Besides, frequent association with multisystem inflammatory syndrome in children (MIS-C) as complication after the recovery has been recorded. Hereby we report the histological findings in the appendix of a female pediatric patient with history of COVID-19 infection.
Case Report: In our case, an 8-year-old female patient presented to the emergency department of our main tertiary hospital in Bahrain with two days history of low grade fever, lower abdominal pain, nausea, and vomiting. She was admitted to the pediatric surgical unit for a suspected acute appendicitis. A diagnostic laparoscopy and laparoscopic appendectomy was performed. The appendix was sent to the histopathology examination which confirmed the diagnosis of acute suppurative appendicitis with focal endarteritis obliterans. Retrospectively history revealed the child was COVID-19 positive three months back.
Conclusion: Microvascular injury in the appendix of our case adds to the preliminary available evidences in the literature indicating that endarteritis obliterans of the gastrointestinal (GI) tract organs could be a complication of the COVID-19 virus infection like in MIS-C which is a known post-infectious complication of the virus.
Keywords: Acute respiratory failure, Appendicitis, Appendectomy, COVID-19, Laparoscopy, Multisystem inflammatory syndrome in children (MIS-C), Safety, SARS-CoV-2, Surgery
SUPPORTING INFORMATION
Acknowledgments
Acknowledgments for the I-Seha System technical staff and radiology department for the contribution of retrieving labs and reports.
Author ContributionsMaryam Fadhel Hammad - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ashok Kumar Malik - Substantial contributions to conception and design, Acquisition of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 Maryam Fadhel Hammad et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
